Education
Ph.D. Systems Biology, Keio University, Japan (2007-2009)
M.S. Bioinformatics, Keio University, Japan (2005-2007)
B.S. Environmental Information, Keio University, Japan (2001-2005)
Professional Positions
Associate Professor, Earth-Life Science Institute/Department of Life Science and Technology, Institute of Science Tokyo, Japan (2020-present)
Project Associate Professor, Earth-Life Science Institute, Tokyo Institute of Technology Japan (2017-present)
Specially Appointed Associate Professor, Earth-Life Science Institute, Tokyo Institute of Technology Japan (2019-2020)
Researcher, Earth-Life Science Institute, Tokyo Institute of Technology Japan (2018-2019)
EON Postdoctoral Fellow, Earth-Life Science Institute, Tokyo Institute of Technology Japan (2016-2018)
Postdoctoral Research Fellow, UARC/NASA Ames Research Center, USA (2013-2016)
JSPS Postdoctoral Fellowship for Research Abroad, NASA Ames Research Center, USA (2011-2013)
JSPS Postdoctoral Fellow, Institute for Advanced Biosciences, Keio University, Japan (2009-2010)
Origin and evolution of enzymes involved in histidine biosynthesis pathway
ヒスチジン合成酵素の起源と進化解析
Development of sequencing techniques for peptides containing non-canonical amino acids using nanochannel-integrated nano-gap devices
ナノギャップシーケンサーを用いた非天然型アミノ酸含有ペプチドの分析基盤の開発
Secondary structure shuffling method for exploring protein structure diversity
二次構造シャッフリング法を用いたタンパク質の構造空間の探索
In vitro co-evolution of RNA-peptide complex
RNAタンパク質複合体の試験管内進化
Directed evolution of CO2 fixation enzyme using protein biosensor
バイオセンサーを用いたCO2固定酵素の指向性進化
Development of biochemical synthesis of amino acids in a cell-free system
無細胞翻訳系とアミノ酸合成系を組み合わせた反応系の構築
Understanding the non-ribosomal origin of biopolymers
非リボソーム型ポリマー合成の起源に迫る
Multiomics analysis of microorganism with a synthetic carbon fixation pathway
人工炭素固定経路を導入した微生物のマルチオミクス解析
Role of RNA modifications in the structure and function of a primordial Peptidyl Transferase Center
原始ペプチジル転移中心におけるRNA修飾の構造と機能への寄与
Evolutionary molecular engineering of the artificial nucleic acid, L-aTNA
人工核酸(L-aTNA)の進化分子工学
Phosphorylation of organic molecules using polyphosphate micro droplets
ポリリン酸微小液滴を用いた有機分子のリン酸化
Peptide interactions with prebiotic membranes
ペプチドと原始膜系の相互作用
RNA-peptide coevolution using aminoacylating ribozyme
アミノアシル化リボザイムを用いたRNA-ペプチド共進化
Nucleotide synthesis in water/supercritical CO2 two-phase environment
超臨界CO2–水二相環境における核酸分子の合成
Chemical synthesis of proto-ribosome substrates
原始リボソームの基質の調査と化学合成
Understanding enzyme diversity by evaluating substrate interaction mode
酵素多様性の理解に向けた基質との相互作用の評価
Dessication resistance of terrestrial cyanobacterium
陸棲藍藻の乾熱耐性の調査
Analysis of the emergent sequences and fold patterns through Random oligonucleotide ligation/decomposition cycle
ランダムオリゴヌクレオチドの重合と分解から生じる配列と構造の解析
Analysis of interaction between lipid membrane and nucleic acids
脂質膜と核酸の相互作用解析
Analysis on structural diversity of phosphate-binding proteins
リン酸結合タンパク質の構造多様性の解析
Partitioning behavior and solubility of amino acids in a supercritical CO₂–water two-phase System
超臨界CO2–水二相環境におけるアミノ酸の分配挙動および溶解度の評価
Detection of RNA Modifications via Nanotechnology Platforms
ナノテクノロジープラットフォームによるRNA修飾の検出
TBD
TBD
Protein Immobilization Using Scaffolding Silk and Evaluation of a Continuous Reaction System
スキャフォルディングシルクを用いたタンパク質固定化及び連続反応系の検証
TBD
TBD
Synthesis and functionalization of polyester droplets as a protocell in supercritical CO₂–alkaline seawater two-phase environment
超臨界CO₂–アルカリ性海水二相環境におけるプロトセルモデルとしてのポリエステル液滴合成と機能獲得
Understanding the sequence/structural bias at the RNA ligation junction
RNAライゲーション部位における配列と構造バイアスの理解
Evolutionary Origins and Diversity of Polyketide Synthases in Aachaea
古細菌におけるポリケチド合成酵素の進化的起源と多様性の解明
Theoretical Investigation of Robustness of rTCAcycle under Environmental Perturbation
環境摂動がrTCAサイクルに与える影響の理論的研究
cell-free reconstitution of nucleotide biosynthesis pathway
無細胞系での核酸合成経路の再構成
技術支援員 (東京科学大学)
研究員 (株式会社MOLCUREより出向)
研究員 (株式会社SyntheticGestaltより出向)
技術支援員
事務支援員